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Recent advances in small molecule fluorescent probes for simultaneous imaging of two bioactive moleculesin live cells and in vivo

Yongqing Zhou, Xin Wang, Wei Zhang, Bo Tang, Ping Li

Frontiers of Chemical Science and Engineering 2022, Volume 16, Issue 1,   Pages 4-33 doi: 10.1007/s11705-021-2041-2

Abstract: Fluorescence imaging associated with small molecular probes has been widely used in the imaging of bioactive

Keywords： bioactive molecules     fluorescent probes     in living cells and in vivo     review    

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Synthesis and properties of water-soluble 1,9-dialkyl-substituted BF

Dan Wu, Gonzalo Durán-Sampedro, Donal F. O’Shea

Frontiers of Chemical Science and Engineering 2020, Volume 14, Issue 1,   Pages 97-104 doi: 10.1007/s11705-019-1828-x

Abstract: Live cell microscopy imaging revealed efficient uptake and intracellular labelling of cells for both, makes the present NIR-active azadipyrromethene derivatives potentially useful as NIR fluorescence imagingprobes for live cells.

Keywords： NIR-fluorophores     live cell imaging     NIR-AZA    

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In vivo imaging of hematopoietic stem cell development in the zebrafish

Panpan Zhang, Feng Liu

Frontiers of Medicine 2011, Volume 5, Issue 3,   Pages 239-247 doi: 10.1007/s11684-011-0123-0

Abstract: imaging is crucial for developmental biology and can further help to follow cell development/differentiationRecent advances in optical imaging techniques has facilitated tracing of the developmental dynamics ofa specific organ, tissue, or even a single cell.The zebrafish is an excellent model for imaging of hematopoiesis due to its transparent embryo at earlyIn this review, we summarize recent studies related to the non-invasive imaging of HSC transgenics,

Keywords： hematopoietic stem cell     hematopoiesis     in vivo imaging     transgenics     zebrafish    

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Fluorescent probes and functional materials for biomedical applications

Frontiers of Chemical Science and Engineering 2022, Volume 16, Issue 10,   Pages 1425-1437 doi: 10.1007/s11705-022-2163-1

Abstract: Due to their simplicity in preparation, sensitivity and selectivity, fluorescent probes have become the analytical tool of choice in a wide range of research and industrial fields, facilitating the rapid detection of chemical substances of interest as well as the study of important physiological and pathological processes at the cellular level. In addition, many long-wavelength fluorescent probes developed have also proven applicable for in vivo biomedical applications including fluorescence-guided disease diagnosis and theranostics (e.g., fluorogenic prodrugs). Impressive progresses have been made in the development of sensing agents and materials for the detection of ions, organic small molecules, and biomacromolecules including enzymes, DNAs/RNAs, lipids, and carbohydrates that play crucial roles in biological and disease-relevant events. Here, we highlight examples of fluorescent probes and functional materials for biological applications selected from the special issues “Fluorescent Probes” and “Molecular Sensors and Logic Gates” recently published in this journal, offering insights into the future development of powerful fluorescence-based chemical tools for basic biological studies and clinical translation.

Keywords： fluorescent probes     imaging     cell     biomedicine     biomolecules    

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Applications for Nanoscale X-Ray Imaging at High Pressure Article

Wendy L. Mao, Yu Lin, Yijin Liu, Jin Liu

Engineering 2019, Volume 5, Issue 3,   Pages 479-489 doi: 10.1016/j.eng.2019.01.006

Abstract:

Coupling nanoscale X-ray transmission microscopy (nanoTXM) with a diamond anvil cell (DAC) has excitingpotential as a powerful three-dimensional probe for non-destructive imaging at high spatial resolutionIn this article, we discuss current developments in high-resolution X-ray imaging and its application

Keywords： X-ray imaging     High pressure     Diamond anvil cell    

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evaluation of renal function using diffusion weighted imaging and diffusion tensor imaging in type 2

Xiaoyan Chen,Wenxia Xiao,Xinchun Li,Jianxun He,Xiaochun Huang,Yuyu Tan

Frontiers of Medicine 2014, Volume 8, Issue 4,   Pages 471-476 doi: 10.1007/s11684-014-0365-8

Abstract:

This work aims to estimate the value of diffusion weighted imaging (DWI) and diffusion tensor imaging

Keywords： type 2 diabetes mellitus     microalbuminuria     diffusion weighted imaging     diffusion tensor imaging     early-stage    

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activated rapid addition and mitochondrial targeting ratiometric fluorescent probes for in vivo cellH2S imaging

Yan Shi, Fangjun Huo, Yongkang Yue, Caixia Yin

Frontiers of Chemical Science and Engineering 2022, Volume 16, Issue 1,   Pages 64-71 doi: 10.1007/s11705-021-2048-8

Abstract: In addition, cell imaging shows that this probe can be used for the mitochondrial targeted detectionFinally, this probe application was verified by imaging H S in nude mice.

Keywords： heterocyclic compound     hydrogen sulfide     ratiometric     mitochondrial targeted    

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First Pig-to-Live Human Xenotransplant Produces Mixed Results

Sarah C.P. Williams

Engineering 2022, Volume 16, Issue 9,   Pages 6-8 doi: 10.1016/j.eng.2022.07.006

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Carbon dots-based fluorescence sensor for two-photon imaging of pH in diabetic mice

Frontiers of Chemical Science and Engineering 2023, Volume 17, Issue 3,   Pages 298-306 doi: 10.1007/s11705-022-2212-9

Abstract: Finally, the CA-CDs has been successfully applied for two-photon imaging of the pH in liver and kidneyImaging results showed that the pH value in kidney of diabetic mice was lower than that of the normal

Keywords： carbon dots     two-photon imaging     pH     diabetic mice    

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Recent Advances in 19Fluorine Magnetic Resonance Imaging with Perfluorocarbon Emulsions Review

Anne H. Schmieder,Shelton D. Caruthers,Jochen Keupp,Samuel A. Wickline,Gregory M. Lanza

Engineering 2015, Volume 1, Issue 4,   Pages 475-489 doi: 10.15302/J-ENG-2015103

Abstract:

The research roots of 19fluorine (19F) magnetic resonance imaging (MRI) dateOver that time span, 1H imaging flourished and was adopted worldwide with an endless arrayof applications and imaging approaches, making magnetic resonance an indispensable pillar of biomedicaldiagnostic imaging.For many years during this timeframe, 19F imaging research continued at a slow pace as the

Keywords： fluorine     magnetic resonance imaging (MRI)     dual-tuned coil     perfluorocarbon     angiogenesis     cell labeling    

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Anefficient quadrature demodulator for medical ultrasound imaging

Hao ZHOU,Yin-fei ZHENG

Frontiers of Information Technology & Electronic Engineering 2015, Volume 16, Issue 4,   Pages 301-310 doi: 10.1631/FITEE.1400205

Abstract: Quadrature demodulation is used in medical ultrasound imaging to derive the envelope and instantaneousIn this paper, we propose an efficient quadrature demodulation method for B-mode and color flow imagingIn the in vivo color flow imaging experiments, the time of the demodulation process was 5.66 ms and 3.36

Keywords： B-mode ultrasound imaging     Color flow imaging     Quadrature demodulation     Finite impulse response filter    

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Light field imaging: models, calibrations, reconstructions,and applications Review

Hao ZHU, Qing WANG, Jingyi YU

Frontiers of Information Technology & Electronic Engineering 2017, Volume 18, Issue 9,   Pages 1236-1249 doi: 10.1631/FITEE.1601727

Abstract: Light field imaging is an emerging technology in computationalphotography areas.Based on innovative designs of the imaging modeland the optical path, light field cameras not only recordFinally,open issues in light field imaging and long-term application prospectsin other natural sciences

Keywords： Light field imaging     Plenoptic function     Imaging model     Calibration     Reconstruction    

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Synthesis and application of superparamagnetic iron oxide nanoparticles in targeted therapy and imaging

Liangqian Tong, Ming Zhao, Shu Zhu, Jing Chen

Frontiers of Medicine 2011, Volume 5, Issue 4,   Pages 379-387 doi: 10.1007/s11684-011-0162-6

Abstract: Superparamagnetic iron oxide (SPIO) nanoparticles have become a popular strategy of cancer treatment and molecular imaging, targeted ligand-conjugated, and/or drug-loaded SPIO nanoparticles, as powerful tools for targeted imagingadvancements in the field of SPIO nanoparticles in terms of synthesis, targeted therapy, and cancer imaging

Keywords： nanoparticles     superparamagnetic iron oxide     targeted therapy     molecular imaging     cancer    

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A highly selective fluorescent probe for real-time imaging of UDP-glucuronosyltransferase 1A8 in living

Frontiers of Chemical Science and Engineering 2022, Volume 16, Issue 1,   Pages 103-111 doi: 10.1007/s11705-021-2064-8

Abstract: Based on this perfect biocompatibility and cell permeability, BDMP was successfully used to image endogenousUGT1A8 in human cancer cell lines (LoVo and HCT15) in real time.

Keywords： UDP-glucuronosyltransferase 1A8     fluorescent probe     subtype selectivity     fluorescence imaging    

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of the mechanisms of acupuncture in the treatment of migraine based on functional magnetic resonance imaging

Frontiers of Medicine   Pages 993-1005 doi: 10.1007/s11684-023-0989-7

Abstract: The functional magnetic resonance imaging (fMRI) data were analyzed for investigating brain changes induced

Keywords： acupuncture     migraine     fMRI     metabolome     proteome    

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Title Author Date Type Operation

Recent advances in small molecule fluorescent probes for simultaneous imaging of two bioactive moleculesin live cells and in vivo

Yongqing Zhou, Xin Wang, Wei Zhang, Bo Tang, Ping Li

Journal Article

Synthesis and properties of water-soluble 1,9-dialkyl-substituted BF

Dan Wu, Gonzalo Durán-Sampedro, Donal F. O’Shea

Journal Article

In vivo imaging of hematopoietic stem cell development in the zebrafish

Panpan Zhang, Feng Liu

Journal Article

Fluorescent probes and functional materials for biomedical applications

Journal Article

Applications for Nanoscale X-Ray Imaging at High Pressure

Wendy L. Mao, Yu Lin, Yijin Liu, Jin Liu

Journal Article

evaluation of renal function using diffusion weighted imaging and diffusion tensor imaging in type 2

Xiaoyan Chen,Wenxia Xiao,Xinchun Li,Jianxun He,Xiaochun Huang,Yuyu Tan

Journal Article

activated rapid addition and mitochondrial targeting ratiometric fluorescent probes for in vivo cellH2S imaging

Yan Shi, Fangjun Huo, Yongkang Yue, Caixia Yin

Journal Article

First Pig-to-Live Human Xenotransplant Produces Mixed Results

Sarah C.P. Williams

Journal Article

Carbon dots-based fluorescence sensor for two-photon imaging of pH in diabetic mice

Journal Article

Recent Advances in 19Fluorine Magnetic Resonance Imaging with Perfluorocarbon Emulsions

Anne H. Schmieder,Shelton D. Caruthers,Jochen Keupp,Samuel A. Wickline,Gregory M. Lanza

Journal Article

Anefficient quadrature demodulator for medical ultrasound imaging

Hao ZHOU,Yin-fei ZHENG

Journal Article

Light field imaging: models, calibrations, reconstructions,and applications

Hao ZHU, Qing WANG, Jingyi YU

Journal Article

Synthesis and application of superparamagnetic iron oxide nanoparticles in targeted therapy and imaging

Liangqian Tong, Ming Zhao, Shu Zhu, Jing Chen

Journal Article

A highly selective fluorescent probe for real-time imaging of UDP-glucuronosyltransferase 1A8 in living

Journal Article

of the mechanisms of acupuncture in the treatment of migraine based on functional magnetic resonance imaging

Journal Article